Pulmonary Compliance and Resistance Analysis Module

The Pulmonary Compliance and Resistance (PCR/PCRP) Analysis Module analyzes pulmonary flow and pulmonary pressure signals derived from either a plethysmograph chamber or a pneumotach, along with pulmonary pressure. Values for these derived signals are calculated on a breath-to-breath basis for each respiratory cycle.  The graph above displays a typical pulmonary flow signal and pulmonary pressure signal with the digitally integrated volume signal.  Validation marks and their explanations are also displayed. The validation marks provide visual, real-time verification of the accuracy of the system.  

The list below describes the parameters calculated by the analysis module either in real-time or during subsequent analysis.

Model PNM-PCR100W

Name		Definition
Num		The number of the respiratory cycle.
PIF, PEF		Peak Inspiratory Flow, Peak Expiratory Flow.
TV, MV		Tidal Volume, Minute Volume
BPM		The number of breaths-per-minute is calculated on a breath-to-breath basis.
IT, ET, TT, AT		Inspiratory Time, Expiratory Time, Total Time, Apnea Time.
Cdyn, Res, Cond		Compliance, Resistance, Conductance.
ResI1, ResI2, ResE1, ResE2		Resistance calculated at various points of inspiration and expiration.
CAvg, RAvg		Compliance and Resistance value averaged.
PInspS(P1), PExpS(P2), Piso1(P3), Piso2(P4)		Pressure value at different time points of flow signal.
Fiso1(F1), Fiso2(F2)		Flow on clearing isovolumic levels during inspiration and expiration.
PEnh		Enhanced Pause. Calculated as: ((ET+AT)/RT-1)*(PEF/PIF). Formula from Noninvasive Measurement of Airway Responsiveness in Allergic Mice Using Barometric Plethysomgraphy Hamelmann et al.
RT		Relaxation Time.
WOBi, WOBe, WOB		Work of Breathing Inspiration, Work of Breathing Expiration and Work of Breathing (sum)
POBi, POBe, POB		Power of Breathing Inspiration, Power of Breathing Expiration and Power of Breathing (rate at which work was performed over inspiration and expiration).
TVe		The difference between the volume at the start of expiration mark and the volume at the point prior to the next cycles start inspiration mark.
AVol		Accumulated volume.
IF50		Inspiratory flow value at the point where the volume signal rises to 50% of the tidal volume.
EF50		Expiratory flow value at the point where the volume signal drops to 50% of the tidal volume.