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Program complex pharmacokinetic and tolerance based infusion protocols including:

  • constant continuous/variable dose
  • circadian rhythm infusion
  • complex dosage simulations

Further, iPRECIO® enables researchers to test the relevance of dosing time or dosing protocol on the therapeutic index of small and large molecules.

The easy to use menu driven iPRECIO®software header information, along with infusion protocol details, are entered and ultimately downloaded to the pump's flash memory. Start Time, End Time, Flow rate (1.0µl/hour to 30.0µl/hour), Constant and Variable infusion mode are programmable. Both Constant and Variable infusion options have Instant or Recovery Mode Infusion settings.

Programmability makes iPRECIO® pumps indispensable for applications where accurate infusion, recovery/washout periods, constant/variable dose or complex circadian infusion studies are necessary.
Infusion Mode Flow Rate Mode Description
1 Instant Infusion Constant Flow Rate The pump starts administration instantly at the pre-programmed start time & date and continues to infuse for the pre-programmed flow rate and duration.
2 Instant Infusion Variable Flow Rate The pump starts administration instantly at the pre-programmed start time & date and continues to infuse at the various pre-programmed flow rate steps and durations.
3 Post Recovery Infusion Contant Flow Rate The pump starts administration after the animals convalescence period following surgery. During the convalescence/recovery period saline is infused at a programmable constant flow rate. On completion of the recovery period the pump operates as described in instant constant flow rate.
4 Post Recovery Infusion Variable Flow Rate The pump starts administration after the animals convalescence period following surgery. During the convalescence/recovery period saline is infused at a programmable constant flow rate. On completion of the recovery period the pump operates as described in instant variable flow rate.

iPRECIO® infusion pumps which are implantable, programmable and refillable will provide benefits of syringe pumps and other implantable pumps combined in one unit. In combination with the physiologic gold standard of telemetry, sophisticated implantable infusion pumps will lead to ever more sensitive and powerful means of detecting drug induced therapeutic and/or adverse effects.


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