实验动物肺功能检测系统(PFT系统)
与人类肺功能检测原理类似,PFT可对麻醉动物进行一系列成组实验,自动检测并实时数据分析,获得相应肺功能生理参数。FRC检测要求动物保持自主呼吸状态,其它测试均可在使用呼吸机辅助呼吸或动物自主呼吸状态下进行。
主要测试:
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气道阻力和动态肺顺应性(RC测试)。
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波义耳定律(Boyle’s Law)功能残气量(FRC测试)。
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准静态肺部容积与肺部压力关系曲线(Pressure-Volume测试)。
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呼吸流速与肺部容积关系(FLow-Volume测试)。
主要参数:FRC功能残气量、FEVx第X秒用力呼气流量、FVC用力肺活量、Cchord准静态肺顺应性、气道阻力RI和动态肺顺应性Cdyn、TLC肺容积、VC肺活量等。
适用动物种属:小鼠、大鼠、豚鼠、兔、犬、猴或其它大动物模型
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参考文献
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